| First Lady | White House | Born-Died | Birthplace |
| Martha Dandridge Washington | 1789-1797 | 1731-1902 | Virginia |
| Abigail Smith Adams | 1797-1801 | 1744-1818 | Massachusetts |
| Martha Wayles Jefferson | Deceased | 1748-1782 | Virginia |
| Dolley Payne Todd | 1809-1817 | 1768-1849 | North Carolina |
| Elizabeth Kortright Monroe | 1817-1825 | 1768-1830 | New York |
| Louisa Johnson Adams | 1825-1829 | 1775-1852 | England |
| Rachel Donelson Jackson | Deceased | 1767-1828 | Virginia |
| Hannah Hoes Van Buren | Deceased | 1783-1819 | New York |
| Anna Symmes Harrison | 1841 | 1775-1864 | New Jersey |
| Letitia Christian Tyler | 1841-1842 | 1790-1842 | Virginia |
| Julia Gardiner Tyler | 1842-1845 | 1820-1889 | New York |
| Sarah Childress Polk | 1845-1849 | 1803-1891 | Tennessee |
| Margaret Smith Taylor | 1849-1850 | 1788-1852 | Maryland |
| Abigail Powers Fillmore | 1850-1853 | 1798-1853 | New York |
| Jane Appleton Pierce | 1853-1857 | 1806-1863 | New Hampshire |
| Mary Todd Lincoln | 1861-1865 | 1830-1882 | Kentucky |
| Eliza McCardle Johnson | 1865-1869 | 1810-1876 | Tennessee |
| Julia Dent Grant | 1869-1877 | 1826-1902 | Missouri |
| Lucy Webb Hayes | 1877-1881 | 1831-1889 | Ohio |
| Lucretia Rudolph Garfield | 1881 | 1832-1918 | Ohio |
| Ellen Herndon Arthur | Deceased | 1837-1880 | Virginia |
| Frances Folsom Cleveland | 1885-1889, 1893-1897 | 1864-1947 | New York |
| Caroline Scott Harrison | 1889-1892 | 1832-1892 | Ohio |
| Ida Saxton McKinley | 1897-1901 | 1847-1907 | Ohio |
| Edith Carow Roosevelt | 1901-1909 | 1861-1948 | Connecticut |
| Helen Herron Taft | 1909-1913 | 1861-1943 | Ohio |
| Ellen Axson Wilson | 1913-1914 | 1860-1914 | Georgia |
| Edith Bolling Wilson | 1915-1921 | 1872-1961 | Virginia |
| Florence Kling Harding | 1921-1923 | 1860-1924 | Ohio |
| Grace Goodhue Coolidge | 1923-1929 | 1879-1957 | Vermont |
| Lou Henry Hoover | 1929-1933 | 1874-1944 | Iowa |
| Anna Eleanor Roosevelt | 1933-1945 | 1884-1962 | New York |
| Bess Wallace Truman | 1945-1953 | 1885-1982 | Missouri |
| Mamie Doud Eisenhower | 1953-1961 | 1896-1979 | Iowa |
| Jacqueline Bouvier Kennedy | 1961-1963 | 1929-1994 | New York |
| Claudia "Lady Bird" Taylor Johnson | 1963-1969 | 1912- | Texas |
| Thelma "Pat" Ryan Nixon | 1969-1974 | 1912-1993 | Nevada |
| Elizabeth "Betty" Bloomer Ford | 1974-1977 | 1918- | Illinois |
| Rosalynn Smith Carter | 1977-1981 | 1927- | Georgia |
| Anne "Nancy" Davis Reagan | 1981-1989 | 1921- | New York |
| Barbara Pierce Bush | 1989-1993 | 1925- | New York |
| Hillary Rodham Clinton | 1993-2001 | 1947- | Illinois |
| Laura Welch Bush | 2001- | 1946- | Texas |
